Try running the Xone analyser software on your computer system (if you're running a PC).  
This would enable you to test your MIDI functionality independently of any third-party software.  

If you're running on a Mac, you could use software such as MIDI Monitor (www.snoize.com) to see that you are sending valid MIDI messages from the mixer.
If it turns out you are not, and you have checked your MIDI channel assignments and settings, please let us know.

What computer system are you running with the mixer, and which software package?
Is there any MIDI activity showing on your software package in response to moving the MIDI controls on your mixer?

There are some tutorial videos on our website here which are very useful in setting up our mixers correctly with various software packages:

www.youtube.com/AllenAndHeathUK